Hydrogen Peroxide → HCID 21352793, compound

HRID 395739Notes

Reaction equation

HRID 395739 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]([CH:28]=[CH:29][CH:30]=1)[C:6]([NH:8][C:9]1[C:10]([NH:15][C:16](=[O:27])[C:17]2[CH:22]=[CH:21][C:20]([C:23]([CH3:26])([CH3:25])[CH3:24])=[CH:19][CH:18]=2)=[CH:11][CH:12]=[CH:13][CH:14]=1)=[O:7])#[N:2].OO.C(=O)([O-])[O-:34].[K+].[K+]>CS(C)=O.O>[C:1]([C:3]1[CH:4]=[C:5]([CH:28]=[CH:29][CH:30]=1)[C:6]([NH:8][C:9]1[C:10]([NH:15][C:16](=[O:27])[C:17]2[CH:18]=[CH:19][C:20]([C:23]([CH3:26])([CH3:25])[CH3:24])=[CH:21][CH:22]=2)=[CH:11][CH:12]=[CH:13][CH:14]=1)=[O:7])(=[O:34])[NH2:2]

Participants

6

Reactant 3

HCID 784Hydrogen PeroxideHCID 11430Potassium CarbonateHCID 10810822HCID 10810822, compound

Product 1

HCID 21352793HCID 21352793, compoundYield 166.6%

Reagents, catalysts & solvents 2

HCID 679Dimethyl SulfoxideSolventHCID 962WaterSolvent

Procedure

To a solution of N1-(3-cyanobenzoyl)-N2-(4-tert-butylbenzoyl)-1,2-benzenediamine (200 mg, 0.5 mmol) in methyl sulfoxide (10 mL) was added 30% hydrogen peroxide solution (0.5 mL, 5.8 mmol) and potassium carbonate (17 mg, 0.13 mmol). After stirring for 24 h, the reaction mixture was diluted with water (20 mL), filtered, washed with water, and dried to give 90 mg (43%) of the title compound as a white solid.

Workup

  1. filtrationfiltered
  2. washwashed with water
  3. customdried

Sources & evidence

ORD record
ord-3040975fdbd445139687b783873d70f7
Source dataset
uspto-grants-2003_08
Patent number
US06605626B2

Reaction notes

Loading…