反应详情

温度

100 °C

A mixture of dimethyl 5-(trifluoromethylsulfonyloxy)isophthalate (2.3 g), dihydroxy-phenylborane (1.23 g) and triethylamine (2.0 4 g) in N,N-dimethylformamide (30 ml) was heated at 100° C. and stirred for 3 hours under nitrogen. After evaporating the solvent, the residue was dissolved in a mixture of dichlomethane (100 ml) and water. The organic layer was successively washed with aqueous 10% sodium carbonate solution and brine, dried over magnesium sulfate and evaporated in vacuo. The residue was crystallized from hexane to afford dimethyl 5-phenylisophthalate (1.07 g).

1. customAfter evaporating the solvent
2. dissolutionthe residue was dissolved in a mixture of dichlomethane (100 ml) and water
3. washThe organic layer was successively washed with aqueous 10% sodium carbonate solution and brine
4. dry with materialdried over magnesium sulfate
5. customevaporated in vacuo
6. customThe residue was crystallized from hexane