Cyanoacetamide → HCID 178462492, compound

HRID 400108Notes

Reaction equation

HRID 400108 reaction equation
[CH2:1]([N:3]1[CH2:9][CH2:8][CH2:7][C:6](=O)[CH2:5][CH2:4]1)[CH3:2].[CH:11](OCC)=O.[C:16]([CH2:18][C:19]([NH2:21])=[O:20])#[N:17].[H-].[Na+]>>[C:16]([C:18]1[C:19]([OH:20])=[N:21][C:6]2[CH2:5][CH2:4][N:3]([CH2:1][CH3:2])[CH2:9][CH2:8][C:7]=2[CH:11]=1)#[N:17]

Participants

5

Reactant 4

HCID 7898CyanoacetamideHCID 8025Ethyl formateHCID 24758Sodium hydrideHCID 18784290HCID 18784290, compound

Product 1

HCID 178462492HCID 178462492, compound

Procedure

Prepared from 1-ethylhexahydro-4-azepinone by reaction with ethyl formate and cyanoacetamide in the presence of sodium hydride.

Sources & evidence

ORD record
ord-8814226c9594406cb3d3ea20a042b38a
Source dataset
uspto-grants-1998_10
Patent number
US05827849

Reaction notes

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