反应详情

温度

0 °C

1.38 g of 50% sodium hydride suspended in oil were added under an inert gas atmosphere to a solution of 5.2 g of paraiodophenol in 30 ml of tetrahydrofuran and after stirring at 0° C., then 6.30 g of N,N-bis-(isopropyl)-2-bromo-acetamide (Preparation 8) were added. After stirring for 2 hours while allowing the temperature to rise to 20° C., the reaction medium was poured into ice-cooled water and filtration was carried out followed by drying to obtain 9.3 g of the expected product.

1. stirringAfter stirring for 2 hours
2. customto rise to 20° C.
3. additionthe reaction medium was poured into ice-
4. temperaturecooled
5. filtrationwater and filtration
6. customby drying