反应详情

温度

27.5 °C

In a round bottom flask, (2 g) 4,4′-dichlorobenzophenone in 4 ml methanol was taken. (1.75 ml) (2 equiv.) tri-methyl orthoformate was added into the reaction mixture and stirred at 25-30° C. Then 0.04 ml perchloric acid (as a catalyst) was added and refluxed for 7.5 hrs. After completion of the reaction ethyl acetate and NaHCO3 solution were added and stirred for 10 min. Then layers were separated and washed the organic layer with water. Dry it over sodium sulfate. Concentrate it on rotavapor to obtain yellow colored liquid product

1. temperaturerefluxed for 7.5 hrs
2. additionwere added
3. stirringstirred for 10 min
4. customThen layers were separated
5. washwashed the organic layer with water
6. dry with materialDry it over sodium sulfate
7. concentrationConcentrate it on rotavapor
8. customto obtain yellow colored liquid product