Diethylamine → 2-Diethylamino-4-methylamino-5-nitro-benzoic acid methyl ester

HRID 410792Notes

Reaction equation

HRID 410792 reaction equation
[CH3:1][O:2][C:3](=[O:16])[C:4]1[CH:9]=[C:8]([N+:10]([O-:12])=[O:11])[C:7]([NH:13][CH3:14])=[CH:6][C:5]=1F.[CH2:17]([NH:19][CH2:20][CH3:21])[CH3:18]>CN(C=O)C>[CH3:1][O:2][C:3](=[O:16])[C:4]1[CH:9]=[C:8]([N+:10]([O-:12])=[O:11])[C:7]([NH:13][CH3:14])=[CH:6][C:5]=1[N:19]([CH2:20][CH3:21])[CH2:17][CH3:18]

Participants

4

Reactant 2

HCID 8021DiethylamineHCID 59395139HCID 59395139, compound

Product 1

HCID 673332942-Diethylamino-4-methylamino-5-nitro-benzoic acid methyl ester

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

2-Diethylamino-4-methylamino-5-nitro-benzoic acid methyl ester (1.2 g) was prepared by following General Procedure A starting from 2-fluoro-4-methylamino-5-nitro-benzoic acid methyl ester (1.0 g) and diethylamine (683 uL) in DMF.

Sources & evidence

ORD record
ord-4ffcdd68e00b4846a811cb034a0d477b
Source dataset
uspto-grants-2014_06
Patent number
US08759535B2

Reaction notes

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