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HRID410941

反应详情

EQUATION

反应方程式

HRID 410941 的结构方程式

REACTANTS

反应物

4
结构：ClCCCl
HCID11

1,2-Dichloroethane

C2H4Cl2

结构：S=C(n1ccnc1)n1ccnc1
HCID80264

Thiocarbonyldiimidazole

C7H6N4S

结构：CCNc1ccc(C(=O)OC)cc1N
HCID12758354

Methyl 3-amino-4-(ethylamino)benzoate

C10H14N2O2

结构：Nc1nc2ccc(Oc3cccnc3)cc2s1
HCID86656876

未命名化合物

PRODUCTS

生成物

1
结构：CCn1c(Nc2nc3ccc(Oc4cccnc4)cc3s2)nc2cc(C(=O)OC)ccc21
HCID86656875

未命名化合物

收率 42.3%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

1-Ethyl-2-[6-(pyridin-3-yloxy)-benzothiazol-2-ylamino]-1H-benzoimidazole-5-carboxylic acid methyl ester (155.0 mg) was prepared by following General Procedure D starting from 3-amino-4-ethylamino-benzoic acid methyl ester (160.0 mg), 6-(pyridin-3-yloxy)-benzothiazol-2-ylamine (200.0 mg), 1,1′-thiocarbonyldiimidazole (200.0 mg), and EDC (200.0 mg) in DMF (2.0 mL).