Methylamine → 64910-48-1

HRID 410948Notes

Reaction equation

HRID 410948 reaction equation
C[C:2]1[C:9](F)=[C:8]([N+:11]([O-:13])=[O:12])[CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[CH3:14][NH2:15]>CN(C=O)C>[CH3:14][NH:15][C:9]1[CH:2]=[C:3]([CH:6]=[CH:7][C:8]=1[N+:11]([O-:13])=[O:12])[C:4]#[N:5]

Participants

4

Reactant 2

HCID 6329MethylamineHCID 67335364Methyl 3-fluoro-4-nitrobenzonitrile

Product 1

HCID 1101939864910-48-1

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

3-Methylamino-4-nitro-benzonitrile (1.58 mg) was prepared by following General Procedure A starting from methyl 3-fluoro-4-nitrobenzonitrile (1.66 g) and methylamine (2 M in THF, 10.0 mL) in DMF. The crude product was used in the next step without further purification.

Workup

  1. customThe crude product was used in the next step without further purification

Sources & evidence

ORD record
ord-8abd64403b5e440bb66ed12735731c2f
Source dataset
uspto-grants-2014_06
Patent number
US08759535B2

Reaction notes

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