Potassium Carbonate → HCID 18536303, compound

HRID 412059Notes

Reaction equation

HRID 412059 reaction equation
Cl[C:2]1[N:11]=[CH:10][CH:9]=[CH:8][C:3]=1[C:4]([O:6][CH3:7])=[O:5].C(=O)([O-])[O-].[K+].[K+].[CH3:18][N:19]1[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1>CN(C=O)C>[CH3:18][N:19]1[CH2:24][CH2:23][N:22]([C:2]2[N:11]=[CH:10][CH:9]=[CH:8][C:3]=2[C:4]([O:6][CH3:7])=[O:5])[CH2:21][CH2:20]1

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 531671-MethylpiperazineHCID 819931Methyl 2-chloronicotinate

Product 1

HCID 18536303HCID 18536303, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

3.4 g of methyl chloronicotinate, 5.5 g of potassium carbonate and 2.0 g of N-methylpiperazine were reacted in 50 ml of DMF analogously to Example 1a, 3.9 g (82%) of the product being obtained.

Workup

  1. custombeing obtained

Sources & evidence

ORD record
ord-15ddcc34377d4837ac9358dfcef4e53e
Source dataset
uspto-grants-2003_05
Patent number
US06562827B1

Reaction notes

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