Hydrochloric Acid → HCID 131723886, compound

HRID 412183Notes

Reaction equation

HRID 412183 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][N:11]([CH2:14][CH2:15][C:16]2[N:20]([CH2:21][C:22]3[CH:27]=[CH:26][C:25]([C:28]#[N:29])=[C:24]([F:30])[CH:23]=3)[CH:19]=[N:18][CH:17]=2)[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:31]>C(OCC)(=O)C>[ClH:31].[ClH:31].[ClH:31].[C:28]([C:25]1[CH:26]=[CH:27][C:22]([CH2:21][N:20]2[C:16]([CH2:15][CH2:14][N:11]3[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]3)=[CH:17][N:18]=[CH:19]2)=[CH:23][C:24]=1[F:30])#[N:29]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 18536174HCID 18536174, compound

Product 1

HCID 131723886HCID 131723886, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

A solution of the product from Step C (6.53 g, 15.8 mmol) in ethyl acetate (20 mL) was saturated with HCl gas. The solution was stirred for 1.5 hours and then concentrated in vacuo to yield the titled compound as a white solid.

Workup

  1. concentrationconcentrated in vacuo

Sources & evidence

ORD record
ord-459173622a3d498d96a8571d2f38df27
Source dataset
uspto-grants-2003_05
Patent number
US06562823B1

Reaction notes

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