1,2-Dibromoethane → HCID 15606616, compound

HRID 414465Notes

Reaction equation

HRID 414465 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([SH:9])=[CH:5][CH:4]=1.[CH2:10](Br)[CH2:11]Br.[C:14](=[O:17])([O-])[O-].[K+].[K+]>CN(C)C=O>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([S:9][CH2:5][CH2:6][S:9][C:11]2[CH:10]=[CH:7][C:8]([O:17][CH3:14])=[CH:3][CH:4]=2)=[CH:5][CH:4]=1

Participants

5

Reactant 3

HCID 78391,2-DibromoethaneHCID 11430Potassium CarbonateHCID 127654-Methoxybenzenethiol

Product 1

HCID 15606616HCID 15606616, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

30 g of 4-methoxythiophenol, 20.2 g of ethylene bromide, 40 g of potassium carbonate, and 40 ml of dimethylformamide were placed in a 300 ml flask, and stirred for 3 hours as the interior of the flask was maintained at a temperature of from 50° C. to 60° C. The reaction mixture was poured into ice-cold water to deposit crystals. The crystals were recrystallized from methanol/ethyl acetate 1/1 (volume ratio) mixture. Melting point: 108°-110° C.

Workup

  1. temperaturewas maintained at a temperature of from 50° C. to 60° C
  2. additionThe reaction mixture was poured into ice-cold water
  3. customThe crystals were recrystallized from methanol/ethyl acetate 1/1 (volume ratio) mixture

Sources & evidence

ORD record
ord-d61075e89c0947d3a0eb4f83a31b4ea1
Source dataset
uspto-grants-1988_12
Patent number
US04792542

Reaction notes

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