Potassium Carbonate → HCID 15549582, compound

HRID 429342Notes

Reaction equation

HRID 429342 reaction equation
Cl[CH2:2][CH2:3][CH:4]1[CH2:8][CH2:7][CH2:6][N:5]1[CH3:9].[Cl:10][C:11]1[CH:12]=[C:13]([SH:18])[CH:14]=[CH:15][C:16]=1[Cl:17].C(=O)([O-])[O-].[K+].[K+]>CN(C=O)C>[Cl:10][C:11]1[CH:12]=[C:13]([S:18][CH2:2][CH2:3][CH:4]2[CH2:8][CH2:7][CH2:6][N:5]2[CH3:9])[CH:14]=[CH:15][C:16]=1[Cl:17]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 799643,4-DichlorobenzenethiolHCID 2850932-(2-Chloroethyl)-1-methylpyrrolidine

Product 1

HCID 15549582HCID 15549582, compoundYield 43%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

2-(2-Chloroethyl)-1-methylpyrrolidine (1.50 g, 10.26 mmole), 3,4-dichlorobenzenethiol (1.82 g, 10.1 mmole), potassium carbonate (14.03 g, 101.6 mmole) and DMF (20 mL) were combined, yielding 0.46 g (4.34 mmole, 43%) of the desired compound.

Sources & evidence

ORD record
ord-6d57402a2f694ec49d248f3020590e1a
Source dataset
uspto-grants-2001_11
Patent number
US06316490B1

Reaction notes

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