Potassium Carbonate → HCID 9816925, compound

HRID 429344Notes

Reaction equation

HRID 429344 reaction equation
Cl[CH2:2][CH2:3][CH:4]1[CH2:8][CH2:7][CH2:6][N:5]1[CH3:9].[Cl:10][C:11]1[CH:16]=[C:15]([OH:17])[CH:14]=[CH:13][C:12]=1[SH:18].C(=O)([O-])[O-].[K+].[K+]>CN(C=O)C>[Cl:10][C:11]1[CH:16]=[C:15]([OH:17])[CH:14]=[CH:13][C:12]=1[S:18][CH2:2][CH2:3][CH:4]1[CH2:8][CH2:7][CH2:6][N:5]1[CH3:9]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 2850932-(2-Chloroethyl)-1-methylpyrrolidineHCID 13909774HCID 13909774, compound

Product 1

HCID 9816925HCID 9816925, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

2-(2-Chloroethyl)-1-methylpyrrolidine (2.85 g, 19.29 mmole), 2-chloro-4-hydroxythiophenol (3.1 g, 19.29 mmole), potassium carbonate (26.7 g, 192.9 mmole) and DMF (30 mL) were combined, yielding 3.2 g (11.77 mmole, 61%).

Workup

  1. customyielding 3.2 g (11.77 mmole, 61%)

Sources & evidence

ORD record
ord-9cccf8308e77455fa20f716db8e035e7
Source dataset
uspto-grants-2001_11
Patent number
US06316490B1

Reaction notes

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