Benzaldehyde → (Z)-Benzaldehyde oxime

HRID 440636Notes

Reaction equation

HRID 440636 reaction equation
[CH:1](=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.[NH2:10][OH:11].C(=O)([O-])[O-].[Na+].[Na+]>CO>[CH:1](=[N:10][OH:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 240BenzaldehydeHCID 10340Sodium CarbonateHCID 443297Hydroxyamine hydrochloride

Product 1

HCID 12143(Z)-Benzaldehyde oximeYield 99.2%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

10.6 g of benzaldehyde, 7.0 g of hydroxylamine hydrochloride and 14.0 g of sodium carbonate were added to 200 ml of methanol and then stirred for 5 hours at normal temperature. The reaction mixture was filtered and then methanol was distilled off under reduced pressure from the filtrate to obtain 12.0 g (Yield 99%) of the title compound (III-1) as a white solid.

Workup

  1. filtrationThe reaction mixture was filtered
  2. distillationmethanol was distilled off under reduced pressure from the filtrate

Sources & evidence

ORD record
ord-233482af162442449f455612d09bae50
Source dataset
uspto-grants-1996_05
Patent number
US05521146

Reaction notes

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