Butyl bromide → HCID 20340027, compound

HRID 444039Notes

Reaction equation

HRID 444039 reaction equation
[Na].[CH2:2]([O:4][C:5]([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH:13]1[N:17]([CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])[C:16](=[O:26])[NH:15][C:14]1=[O:27])=[O:6])[CH3:3].[CH2:28](Br)[CH2:29][CH2:30][CH3:31]>C(O)C>[CH2:28]([N:15]1[C:14](=[O:27])[CH:13]([CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][C:5]([O:4][CH2:2][CH3:3])=[O:6])[N:17]([CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])[C:16]1=[O:26])[CH2:29][CH2:30][CH3:31]

Participants

5

Reactant 3

HCID 8002Butyl bromideHCID 5360545SodiumHCID 12788655HCID 12788655, compound

Product 1

HCID 20340027HCID 20340027, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of sodium (308 mg) in ethanol (40 ml) was added 5-(6-ethoxycarbonylhexyl)-1-octylhydantoin, followed by butyl bromide (1.8 g), and the solution was refluxed for 24 hours. The solvent was evaporated, water was added and the insoluble oil was extracted with ether. The washed and dried extract was evaporated to give 3-butyl-5-(6-ethoxycarbonylhexyl)-1-octyl hydantoin.

Workup

  1. temperaturethe solution was refluxed for 24 hours
  2. customThe solvent was evaporated
  3. additionwater was added
  4. extractionthe insoluble oil was extracted with ether
  5. washThe washed
  6. customdried
  7. extractionextract
  8. customwas evaporated

Sources & evidence

ORD record
ord-a5a36e58513a43f7b520f355a78bc914
Source dataset
uspto-grants-1981_04
Patent number
US04262128

Reaction notes

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