Lithium Hydroxide → HCID 12912741, compound

HRID 444470Notes

Reaction equation

HRID 444470 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7](Cl)=[CH:6][N:5]=1)([O-:3])=[O:2].[Cl:11][C:12]1[CH:17]=[CH:16][C:15]([SH:18])=[CH:14][CH:13]=1.[OH-].[Li+].CN(C=O)C>O>[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([S:18][C:15]2[CH:16]=[CH:17][C:12]([Cl:11])=[CH:13][CH:14]=2)=[CH:6][N:5]=1)([O-:3])=[O:2]

Participants

6

Reactant 4

HCID 3939Lithium HydroxideHCID 6228DimethylformamideHCID 7815p-ChlorothiophenolHCID 2598065-Chloro-2-nitropyridine

Product 1

HCID 12912741HCID 12912741, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

2-Nitro-5-chloropyridine (9.5 grams), 4-chlorothiophenol (8.7 grams), and lithium hydroxide (4 grams) were mixed in 100 ml. of DMF and the reaction mixture was stirred overnight (about 18 hours) at room temperature. The reaction mixture was then poured into water and the product separated by filtration and crystallized from ethanol-hexanes, yield, 10.0 grams, m.p., 96°-98° C.

Workup

  1. customthe product separated by filtration
  2. customcrystallized from ethanol-hexanes
  3. customyield
  4. customm.p., 96°-98° C.

Sources & evidence

ORD record
ord-59219e31105d4d478d72800c39063248
Source dataset
uspto-grants-1981_04
Patent number
US04264605

Reaction notes

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