Hydrochloric Acid → 2-Chloro-3'-sulfamoylacetophenone

HRID 461164Notes

Reaction equation

HRID 461164 reaction equation
[S:1]([C:5]1[CH:6]=[C:7]([C:11](=[O:15])[CH:12]=[N+]=[N-])[CH:8]=[CH:9][CH:10]=1)(=[O:4])(=[O:3])[NH2:2].[ClH:16].C(O)C>COCCOCCOC>[Cl:16][CH2:12][C:11]([C:7]1[CH:8]=[CH:9][CH:10]=[C:5]([S:1](=[O:4])(=[O:3])[NH2:2])[CH:6]=1)=[O:15]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 537058143'-Sulfamoyl-diazoacetophenone

Product 1

HCID 220071722-Chloro-3'-sulfamoylacetophenone

Reagents, catalysts & solvents 1

HCID 8150DiglymeSolvent

Procedure

9.5 g of 3'-sulfamoyl-diazoacetophenone were reacted as prescribed in Example 66b) with 37% HCl in diethylene glycol dimethyl ether and worked up. Colorless crystals, melting point: 118° C (from a small amount of ethanol).

Sources & evidence

ORD record
ord-1ccf32dd43ee4e64bae49bae7b48c108
Source dataset
uspto-grants-1977_12
Patent number
US04061761

Reaction notes

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