Methanol → 2,3-Dihydro-1H-inden-1-one oxime

HRID 464652Notes

Reaction equation

HRID 464652 reaction equation
[C:1]1(=O)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1.Cl.[NH2:12][OH:13].C(=O)([O-])[O-].[K+].[K+].CO>O>[OH:13][N:12]=[C:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1

Participants

6

Reactant 4

HCID 887MethanolHCID 67351-IndanoneHCID 11430Potassium CarbonateHCID 443297Hydroxyamine hydrochloride

Product 1

HCID 3023232,3-Dihydro-1H-inden-1-one oxime

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

A mixture of 1-indanone (100 g), hydroxylamine HCl (183 g), potassium carbonate (183 g), methanol (1700 ml) and water (170 ml) was heated at reflux for 18 hours, then cooled and poured into water. The title compound was filtered, washed with water and air-dried.

Workup

  1. temperaturewas heated
  2. temperatureat reflux for 18 hours
  3. temperaturecooled
  4. filtrationThe title compound was filtered
  5. washwashed with water
  6. customair-dried

Sources & evidence

ORD record
ord-54390f6c62fb4669b8d72df83c6b7e0d
Source dataset
uspto-grants-1985_10
Patent number
US04548943

Reaction notes

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