反应详情

To a suspension of 5-phenyltetrazole (5 g; 34 mmole), stirring in 55 mL of acetone, was added 3.6 g of triethylamine (36 mmoles). The mixture was aged for 15 minutes after which triphenylmethylchloride (10.0 g; 36 mmoles) in 20 mL of THF was added; the temperature rose 8°-10° C. After stirring for 1 hour, 75 mL of H2O was added and the mixture stirred for 1 hour. After filtration, washing with water and drying in vacuo at 70° C., 13.3 g of 18a was obtained.

1. customrose 8°-10° C
2. stirringthe mixture stirred for 1 hour
3. filtrationAfter filtration
4. washwashing with water
5. customdrying in vacuo at 70° C.