Hydrochloric Acid → 2H-Pyran, tetrahydro-2-(4-pentenyloxy)-
Reaction equation
Cl.[O:2]1[CH:7]=[CH:6][CH2:5][CH2:4][CH2:3]1.[CH2:8]([OH:13])[CH2:9][CH2:10][CH:11]=[CH2:12]>>[CH2:8]([O:13][CH:7]1[CH2:6][CH2:5][CH2:4][CH2:3][O:2]1)[CH2:9][CH2:10][CH:11]=[CH2:12]Participants
4
Procedure
Concentrated HCl (0.03 ml) was added dropwise over 25 minutes (slightly exothermic) to a solution of dihydropyran (5.37 g, 64 mmol) and 4-penten-1-ol (5.0 g, 58 mmol) while stirring. At RT the reaction mixture was stirred for two hours. The solution was washed with a saturated sodium carbonate solution and dried over anhydrous potassium carbonate, thus affording 8.6 g (87% yield) of a light yellow oil.
Workup
- stirringAt RT the reaction mixture was stirred for two hours
- washThe solution was washed with a saturated sodium carbonate solution
- dry with materialdried over anhydrous potassium carbonate
Sources & evidence
- ORD record
- ord-03498f6e8734445cac04c9178409e5ca
- Source dataset
- uspto-grants-1989_12
- Patent number
- US04889941
Reaction notes
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