反应详情

A mixture of N-(1-methylhexyl)aniline (76 parts), 1-bromobutane (66 parts), anhydrous potassium carbonate (65 parts) and DMF (150 parts) was stirred while heating under reflux for 41 hours. An additional quantity of 1-bromo butane (44 parts) was added and the mixture stirred while heating under reflux for a further 19 hours. The cooled mixture was poured into water (400 parts) and the organic phase separated. The aqueous phase was extracted with toluene, the organic phases and toluene extract were combined and washed with water (2×100 parts) before evaporating to leave N-butyl-N-(1-methylhexyl)aniline (72.8 parts, 44%) which was purified by vacuum distillation to give N-butyl-N-(1-methylhexyl)aniline b.pt 73-80° C., 2.6 mm Hg. [Dye (1)].

1. temperaturewhile heating
2. temperatureunder reflux for 41 hours
3. stirringthe mixture stirred
4. temperaturewhile heating
5. temperatureunder reflux for a further 19 hours
6. customthe organic phase separated
7. extractionThe aqueous phase was extracted with toluene
8. extractionthe organic phases and toluene extract
9. washwashed with water (2×100 parts)
10. custombefore evaporating