2-Bromoaniline → HCID 69677023, compound

HRID 480930Notes

Reaction equation

HRID 480930 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([NH:9][S:10](Cl)(=[O:12])=[O:11])=[C:5]([O:14][CH3:15])[CH:4]=1)#[N:2].[Br:16][C:17]1[CH:23]=[CH:22][CH:21]=[CH:20][C:18]=1[NH2:19]>CN(C=O)C>[C:1]([C:3]1[CH:8]=[CH:7][C:6]([NH:9][S:10]([NH:19][C:18]2[CH:20]=[CH:21][CH:22]=[CH:23][C:17]=2[Br:16])(=[O:12])=[O:11])=[C:5]([O:14][CH3:15])[CH:4]=1)#[N:2]

Participants

4

Reactant 2

HCID 119922-BromoanilineHCID 18766652HCID 18766652, compound

Product 1

HCID 69677023HCID 69677023, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

To a solution of N-(4-cyano-2-methoxyphenyl)-sulfamoyl chloride (1 mmol) in DMF (1 mL) is added 2-bromoaniline (1 mmol). Upon completion of the reaction, an aqueous work up is performed. The crude material will be purified by either recrystalization or chromatography to give N-(4-Cyano-2-methoxyphenyl)-N′-(2-bromophenyl) sulfamide.

Workup

  1. customUpon completion of the reaction
  2. customThe crude material will be purified by either recrystalization or chromatography

Sources & evidence

ORD record
ord-8fc27b3828b24c76b31f95b5b8ba0beb
Source dataset
uspto-grants-2003_11
Patent number
US06653347B2

Reaction notes

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