反应详情

温度

5 °C

A solution of the product from Example 102 (0.172 g, 0.63 mmol) in 4 mL of aqueous 3N HCl solution was heated at reflux for 2 hours. The hot solution was treated with charcoal and filtered. The filtrate was cooled to 5° C. and the solid which formed was collected by filtration and dried at 90° C. under vacuum to give the title compound as a white solid (83 mg, 43% yield), mp=323-330° C.

1. temperatureat reflux for 2 hours
2. filtrationfiltered
3. customthe solid which formed
4. filtrationwas collected by filtration
5. customdried at 90° C. under vacuum