1,2-Ethanedithiol → 4-Methoxyphenyl-1,3-dithiolane

HRID 482782Notes

Reaction equation

HRID 482782 reaction equation
[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:6]([CH:7]=O)=[CH:5][CH:4]=1.[CH2:11]([SH:14])[CH2:12][SH:13]>CCCCCC>[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:6]([CH:7]2[S:14][CH2:11][CH2:12][S:13]2)=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 109021,2-EthanedithiolHCID 312444-Methoxybenzaldehyde

Product 1

HCID 231754-Methoxyphenyl-1,3-dithiolaneYield 99.5%

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

Following the general procedure as in Example 1, 25 gm (0.184 moles) of 4-methoxybenzaldehyde and 17.3 gm (0.184 moles) of 1,2-ethanedithiol gave, after crystallization from hexane, 39.3 gm (0.183 moles) of a white colored solid (96% yield) m.p. 62°-63° C. Elemental analysis for C10H12OS2 :

Workup

  1. customgave

Sources & evidence

ORD record
ord-fac1300a410d435390d745fc79f7633a
Source dataset
uspto-grants-1986_03
Patent number
US04575565

Reaction notes

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