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HRID483204

反应详情

EQUATION

反应方程式

HRID 483204 的结构方程式

REACTANTS

反应物

3
结构：COC(=O)/C=C(/C)N
HCID643918

2-Butenoic acid, 3-amino-, methyl ester, (2Z)-

C5H9NO2

结构：O=Cc1cc([N+](=O)[O-])ccc1F
HCID2734770

2-Fluoro-5-nitrobenzaldehyde

C7H4FNO3

结构：CC(=O)CC(=O)OCCN(C)Cc1ccccc1
HCID11776829

2-[Methyl(phenylmethyl)amino]ethyl 3-oxobutanoate

C14H19NO3

PRODUCTS

生成物

1
结构：COC(=O)C1=C(C)NC(C)=C(C(=O)OCCN(C)Cc2ccccc2)C1c1cc([N+](=O)[O-])ccc1F
HCID10051569

未命名化合物

收率 40%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)O
溶剂HCID3776

Isopropanol

C3H8O

PROCEDURE

实验过程

A mixture of 170 mg of 2-fluoro-5-nitrobenzaldehyde, 126 mg of methyl 3-aminocrotonate and 253 mg of 2-(N-benzyl-N-methylamino)ethyl acetoacetate in 1 ml of 2-propanol was reacted and then purified in the same way as in Example 9 to yield 200 mg of the desired compound (144).

WORKUP

后处理

  1. customwas reacted
  2. custompurified in the same way as in Example 9