反应详情

A well stirred mixture of 100 g of methyl 4-hydroxybenzoate, 182.25 g of tetradecylbromide, 136.26 g of potassium carbonate and 4.93 g of sodium iodide in 1-liter of acetone is refluxed for 48 hours. The mixture is poured into ice water, the solid collected and washed with water. The solid is dissolved in chloroform and washed with 1N sodium hydroxide, dried and evaporated to a residue which is crystallized from hexanes to give 18.5 g of the desired product as a white solid, m.p. 64°-66° C.

1. temperatureis refluxed for 48 hours
2. customthe solid collected
3. washwashed with water
4. dissolutionThe solid is dissolved in chloroform
5. washwashed with 1N sodium hydroxide
6. customdried
7. customevaporated to a residue which
8. customis crystallized from hexanes