Hydrochloric Acid → HCID 67856145, compound

HRID 483805Notes

Reaction equation

HRID 483805 reaction equation
C(OC([NH:8][C:9](=[O:15])[C@H:10]([CH2:12][S:13][CH3:14])[NH2:11])=O)(C)(C)C.[CH2:16]1[O:25][C:24]2[CH:23]=[CH:22][C:20]([NH2:21])=[CH:19][C:18]=2[O:17]1.[ClH:26]>C(OCC)(=O)C>[ClH:26].[CH3:14][S:13][CH2:12][C@@H:10]([C:9]([NH2:8])=[O:15])[NH2:11].[CH2:16]1[O:25][C:24]2[CH:23]=[CH:22][C:20]([NH2:21])=[CH:19][C:18]=2[O:17]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 67856230HCID 67856230, compound

Product 1

HCID 67856145HCID 67856145, compoundYield 83%

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

After 1.83 g of the [(3,4-methylenedioxy)aniline]-N-t-butoxycarbonyl-S-methylcysteinamide obtained above in (A) were dissolved in 20 ml of ethyl acetate, hydrochloric acid gas was ebulated at room temperature under stirring until no fresh precipitate was formed. The colorless precipitate so obtained was collected by filtration and then dried, whereby 1.25 g of [(3,4-methylenedioxy)aniline]-S-methylcysteinamide hydrochloride were obtained (yield: 83%).

Workup

  1. customwas ebulated at room temperature
  2. customwas formed
  3. customThe colorless precipitate so obtained
  4. filtrationwas collected by filtration
  5. customdried

Sources & evidence

ORD record
ord-d8e691ef92c042fc98a597a41baef450
Source dataset
uspto-grants-1993_07
Patent number
US05227398

Reaction notes

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