Sodium Iodide → HCID 13092097, compound

HRID 485170Notes

Reaction equation

HRID 485170 reaction equation
[C:1]([NH:4][C:5]1[CH:12]=[CH:11][CH:10]=[C:9]([OH:13])[C:6]=1[CH:7]=[O:8])(=[O:3])[CH3:2].Br[CH2:15][C:16]1[CH:26]=[CH:25][C:19]([C:20]([O:22][CH2:23][CH3:24])=[O:21])=[CH:18][CH:17]=1.C(=O)([O-])[O-].[K+].[K+].[I-].[Na+]>C(O)C>[C:1]([NH:4][C:5]1[C:6]([CH:7]=[O:8])=[C:9]([CH:10]=[CH:11][CH:12]=1)[O:13][CH2:15][C:16]1[CH:26]=[CH:25][C:19]([C:20]([O:22][CH2:23][CH3:24])=[O:21])=[CH:18][CH:17]=1)(=[O:3])[CH3:2]

Participants

6

Reactant 4

HCID 5238Sodium IodideHCID 11430Potassium CarbonateHCID 954261Ethyl 4-(bromomethyl)benzoateHCID 20271536HCID 20271536, compound

Product 1

HCID 13092097HCID 13092097, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

2-Acetylamino-6-hydroxybenzaldehyde (0.45 g, 0.0025 M), ethyl 4-bromomethylbenzoate (0.51 g, 0.0025 M), anhydrous potassium carbonate (0.38 g), sodium iodide (50 mg) and 95% ethanol (20 ml) were reacted together (41/2 hr) to give ethyl 4-(3-acetylamino-2-formylphenoxymethyl)benzoate, m.p. 116°-119° C. (ethanol). (Found: C, 66.76; H, 5.61; N, 3.87%. C19H19NO5 requires C, 66,85; H, 5.61; N, 4.10%).

Sources & evidence

ORD record
ord-c5d0d353ee1b4f158b356e6b71272c56
Source dataset
uspto-grants-1985_08
Patent number
US04535183

Reaction notes

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