Hydrochloric Acid → HCID 178427277, compound

HRID 485965Notes

Reaction equation

HRID 485965 reaction equation
[OH:1][CH2:2][CH2:3][N:4]=[C:5]([OH:19])[C:6]1[C:7](=[C:11]([Cl:18])[C:12](Cl)=[C:13]([Cl:16])[C:14]=1[Cl:15])[C:8]([OH:10])=[O:9].[CH3:20][C:21]1[CH:26]=[CH:25][C:24]([SH:27])=[CH:23][CH:22]=1.C(=O)([O-])[O-].[K+].[K+].Cl>O1CCCC1>[OH:1][CH2:2][CH2:3][N:4]=[C:5]([OH:19])[C:6]1[C:7](=[C:11]([Cl:18])[C:12]([S:27][C:24]2[CH:25]=[CH:26][C:21]([CH3:20])=[CH:22][CH:23]=2)=[C:13]([Cl:16])[C:14]=1[Cl:15])[C:8]([OH:10])=[O:9]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 78114-MethylbenzenethiolHCID 11430Potassium CarbonateHCID 178524541HCID 178524541, compound

Product 1

HCID 178427277HCID 178427277, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

2 g (6.08 millimols) of tetrachlorophthalic acid N-2-hydroxyethylimide, 0.79 g (6.38 millimols) of p-thiocresol, 2.52 g (18.24 millimols) of potassium carbonate and 20 ml of tetrahydrofuran are stirred at 25° C. for 20 hours. The mixture is acidified with dilute HCl solution and extracted with methylene chloride and the extracts are dried over sodium sulfate. After recrystallisation from toluene, 1.41 g (56% of theory) of the title compound are obtained: melting point 205°-9° C.

Workup

  1. extractionextracted with methylene chloride
  2. dry with materialthe extracts are dried over sodium sulfate
  3. customAfter recrystallisation from toluene, 1.41 g (56% of theory) of the title compound
  4. customare obtained

Sources & evidence

ORD record
ord-ff01f53546524b868d30cb808cb8aed0
Source dataset
uspto-grants-1985_08
Patent number
US04537977

Reaction notes

Loading…