Triethylamine → 145592-12-7

HRID 487009Notes

Reaction equation

HRID 487009 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:6]=[C:7]([Cl:9])[CH:8]=1)[NH2:5].Cl[C:11]([C:13]([O:20][CH3:21])([CH3:19])[C:14]([O:16][CH2:17][CH3:18])=[O:15])=[O:12].C(N(CC)CC)C>>[Cl:1][C:2]1[CH:3]=[C:4]([NH:5][C:11](=[O:12])[C:13]([O:20][CH3:21])([CH3:19])[C:14]([O:16][CH2:17][CH3:18])=[O:15])[CH:6]=[C:7]([Cl:9])[CH:8]=1

Participants

4

Reactant 3

HCID 8471TriethylamineHCID 122813,5-DichloroanilineHCID 19096847Ethyl 2-(chlorocarbonyl)-2-methoxypropionate

Product 1

HCID 19096872145592-12-7Yield 50%

Procedure

3,5-Dichloroaniline (3.33 grams, 0.02 mole), ethyl 2-(chlorocarbonyl)-2-methoxypropionate (4.0 grams, 0.02 mole), prepared in Example LXII Part C, and triethylamine (2.08 grams, 0.02 mole) were reacted in a manner similar to the procedure described in Example I to give 4.40 grams (0.01 mole) of ethyl 3-[(3,5-dichlorophenyl)amino]-2-methoxy-2-methyl-3-oxopropanoate having a melting point of 72° C.-75° C. Elemental analysis of the product indicated the following:

Workup

  1. customwere reacted in a manner similar to the procedure

Sources & evidence

ORD record
ord-143ed248f74b43038ab64b7ef1a3d970
Source dataset
uspto-grants-1994_03
Patent number
US05292937

Reaction notes

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