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HRID489649

反应详情

EQUATION

反应方程式

HRID 489649 的结构方程式

REACTANTS

反应物

2
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：CC(C)(C)OC(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCC(c2ccccc2NS(C)(=O)=O)CC1
HCID23587436

未命名化合物

PRODUCTS

生成物

1
结构：CS(=O)(=O)Nc1ccccc1C1CCN(C(=O)[C@H](N)Cc2ccc(Cl)cc2)CC1
HCID69140350

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCOC(C)=O
溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

The title compound was prepared according to the procedure described in Step (e) using N-[(1R)-1-[(4-chlorophenyl)methyl]-2-(4-{2-[(methylsulfonyl)-amino]phenyl}piperidyl)-2-oxoethyl](tert-butoxy)-carboxamide (Step f) (250 mg, 0.50 mmol) and a saturated soln of HCl in EtOAc (10 mL). The title compound (HCl salt) was isolated by filtration as a white solid (195 mg, 83%). MS (ESI, pos. ion) m/z: 473 (M+1). Calc'd for C21H27Cl2N3O3S: 472.43.

WORKUP

后处理

  1. customThe title compound was prepared