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HRID489669

反应详情

EQUATION

反应方程式

HRID 489669 的结构方程式

REACTANTS

反应物

2
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：CC(C)(C)OC(=O)N1CCC(c2ccccc2C(F)(F)F)CC1
HCID22266189

未命名化合物

PRODUCTS

生成物

1
结构：Cl.FC(F)(F)c1ccccc1C1CCNCC1
HCID21936970

4-[2-(Trifluoromethyl)phenyl]piperidine--hydrogen chloride (1/1)

C12H15ClF3N

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCOC(C)=O
溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

The title compound was prepared according to the procedure described in Example 1 (Step e) from tert-butyl 4-[2-(trifluoromethyl)phenyl]piperidine carboxylate (Step b) (1.64 g, 5 mmol) and satd HCl in EtOAc (50 m[). The title compound was obtained as a white solid (1.32 g). MS (ESI, pos. ion) m/z: 230 (M+1); MS (ESI, neg. ion) m/z: 228 (M−1). Calc'd for C12H15CF3N: 265.70.

WORKUP

后处理

  1. customThe title compound was prepared