Isopropanol → HCID 86619915, compound

HRID 495253Notes

Reaction equation

HRID 495253 reaction equation
COC1C=CC([P:9]([C:12]2C=CC(OC)=CC=2)(=[O:11])[OH:10])=CC=1.[OH-:20].[CH2:21]([N+:25]([CH2:34][CH2:35][CH2:36][CH3:37])([CH2:30][CH2:31][CH2:32][CH3:33])[CH2:26][CH2:27][CH2:28][CH3:29])[CH2:22][CH2:23][CH3:24].C[CH:39]([OH:41])C>O>[OH:20][CH2:12][P:9]([CH2:39][OH:41])(=[O:11])[O-:10].[CH2:34]([N+:25]([CH2:21][CH2:22][CH2:23][CH3:24])([CH2:26][CH2:27][CH2:28][CH3:29])[CH2:30][CH2:31][CH2:32][CH3:33])[CH2:35][CH2:36][CH3:37]

Participants

5

Reactant 3

HCID 3776IsopropanolHCID 624223Bis(4-methoxyphenyl)phosphinic acidHCID 2723671Tetrabutylammonium Hydroxide

Product 1

HCID 86619915HCID 86619915, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

To a flask were added 2.0 g bis(4-methoxyphenyl)phosphinic acid, 3.0 g of a 55-60% solution of tetrabutylammonium hydroxide in water, 2.0 g of water and 18 ml 2-propanol. After heating to 50 C under nitrogen for 1 hour, the solvent was removed and another 20 ml of 2-propanol were added and removed by distillation under reduced pressure. A waxy solid was obtained.

Workup

  1. temperatureAfter heating to 50 C under nitrogen for 1 hour
  2. customthe solvent was removed
  3. additionanother 20 ml of 2-propanol were added
  4. customremoved by distillation under reduced pressure
  5. customA waxy solid was obtained

Sources & evidence

ORD record
ord-5cd1fe7a1e804b33aa0912df3eab481a
Source dataset
uspto-grants-2009_05
Patent number
US07538931B2

Reaction notes

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