Benzyl Bromide → HCID 9165613, compound

HRID 502966Notes

Reaction equation

HRID 502966 reaction equation
[CH:1]1([NH:4][C:5](=[O:13])[C:6]2[CH:11]=[CH:10][C:9]([OH:12])=[CH:8][CH:7]=2)[CH2:3][CH2:2]1.[CH2:14](Br)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1.C(=O)([O-])[O-].[K+].[K+]>CN(C=O)C>[CH2:14]([O:12][C:9]1[CH:10]=[CH:11][C:6]([C:5]([NH:4][CH:1]2[CH2:2][CH2:3]2)=[O:13])=[CH:7][CH:8]=1)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

5

Reactant 3

HCID 7498Benzyl BromideHCID 11430Potassium CarbonateHCID 28390708HCID 28390708, compound

Product 1

HCID 9165613HCID 9165613, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

N-Cyclopropyl-4-hydroxybenzamide was stirred with benzyl bromide and potassium carbonate in DMF at room temperature to obtain 4-(benzyloxy)-N-cyclopropylbenzamide.

Sources & evidence

ORD record
ord-26f15dfd90ff41eebad11ba9ced27ef4
Source dataset
uspto-grants-2010_08
Patent number
US07776897B2

Reaction notes

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