Maleimide → N-(3-Phenylpropyl)maleimide

HRID 505482Notes

Reaction equation

HRID 505482 reaction equation
C1C=CC(P(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1.CC(OC(/N=N/C(OC(C)C)=O)=O)C.[C:34]1([CH2:40][CH2:41][CH2:42]O)[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1.[C:44]1(=[O:50])[NH:48][C:47](=[O:49])[CH:46]=[CH:45]1>>[C:34]1([CH2:40][CH2:41][CH2:42][N:48]2[C:44](=[O:50])[CH:45]=[CH:46][C:47]2=[O:49])[CH:35]=[CH:36][CH:37]=[CH:38][CH:39]=1

Participants

5

Reactant 4

HCID 10935MaleimideHCID 11776TriphenylphosphineHCID 31234BenzenepropanolHCID 5363146Diisopropyl azodicarboxylate

Product 1

HCID 576189N-(3-Phenylpropyl)maleimide

Procedure

Reagents: Ph3P (0.65 g, 2.5 mmol), DIAD (0.5 ml, 2.5 mmol), 3-phenyl-1-propanol (0.48 ml, 3.75 mmol) and maleimide (0.24 g, 2.5 mmol).

Sources & evidence

ORD record
ord-16689c06d4c247388d4ec31af3c99e1e
Source dataset
uspto-grants-2010_08
Patent number
US07781463B2

Reaction notes

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