Maleimide → N-(5-phenylpentyl)maleimide

HRID 505483Notes

Reaction equation

HRID 505483 reaction equation
C1C=CC(P(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1.CC(OC(/N=N/C(OC(C)C)=O)=O)C.[C:34]1([CH2:40][CH2:41][CH2:42][CH2:43][CH2:44]O)[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1.[C:46]1(=[O:52])[NH:50][C:49](=[O:51])[CH:48]=[CH:47]1>>[C:34]1([CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][N:50]2[C:46](=[O:52])[CH:47]=[CH:48][C:49]2=[O:51])[CH:35]=[CH:36][CH:37]=[CH:38][CH:39]=1

Participants

5

Reactant 4

HCID 10935MaleimideHCID 11776TriphenylphosphineHCID 615235-Phenyl-1-pentanolHCID 5363146Diisopropyl azodicarboxylate

Product 1

HCID 6539157N-(5-phenylpentyl)maleimide

Procedure

Reagents: Ph3P (0.65 g, 2.5 mmol), DIAD (0.5 ml, 2.5 mmol), 5-phenyl-1-pentanol (0.63 ml, 3.75 mmol) and maleimide (0.24 g, 2.5 mmol).

Sources & evidence

ORD record
ord-e202a3db8f24469ca3c14bc2dd819ccb
Source dataset
uspto-grants-2010_08
Patent number
US07781463B2

Reaction notes

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