HRID513556

反应详情

EQUATION

反应方程式

HRID 513556 的结构方程式

AUXILIARIES

试剂、催化剂与溶剂

1

PROCEDURE

实验过程

In a similar fashion using route 1 general procedure 4, N-(5-fluoro-quinolin-8-yl)-2-nitro-4-trifluoromethyl-benzenesulfonamide (Intermediate 248) (0.42 g, 1.01 mmol), SnCl2 (0.96 g, 5.06 mmol), 6N HCl (cat.) and EtOH (6 ml) at 85° C. for 24 h gave the title compound (200 mg, 52%).

WORKUP

后处理

  1. customat 85° C.
  2. customfor 24 h