反应详情

300 mg (1.49 mmol) 2-Bromo-3-hydroxy-benzaldehyde, 302 mg (2.24 mmol) (bromomethyl)cyclopropane and 412 mg (2.99 mmol) K2CO3 in 3 mL DMF are stirred at 80° C. over night. Afterwards the reaction mixture is diluted with water and extracted with EtOAc. The organic layer is separated and dried over Na2SO4, filtered and the solvent is removed in vacuo.

1. extractionextracted with EtOAc
2. customThe organic layer is separated
3. dry with materialdried over Na2SO4
4. filtrationfiltered
5. customthe solvent is removed in vacuo