反应详情

温度

60 °C

A mixture of nortropine (381.6 mg), 1-bromo-3-fluoropropane (634.4 mg) and triethylamine (0.42 ml) in DMF (7.5 ml) was heated to 60° C. and stirred at this temperature for 10 h. The solvent was then removed in vacuo. The product with the molecular weight of 187.26 (C10H18FNO) was obtained in this way; MS (ESI): 188 (M+H+).

1. customThe solvent was then removed in vacuo
2. customThe product with the molecular weight of 187.26 (C10H18FNO) was obtained in this way