反应详情

温度

50 °C

A mixture of methyl 4-hydroxy-benzoate (10.0 g, 0.066 mol) and potassium carbonate (12 g, 0.086 mol), were taken in acetone (50 ml) and heated at 50° C. for 1 hour. To the reaction mixture benzyl bromide (8.2 ml, 0.072 mol) was added. The mixture was heated at 80° C. for 5 hours. The mixture was cooled to room temperature and filtered through sintered funnel, washed with acetone. Solvent was removed to obtain pure 4-benzyloxy-benzoic acid methyl ester as white solid (16 g, 100%).

1. temperatureThe mixture was heated at 80° C. for 5 hours
2. temperatureThe mixture was cooled to room temperature
3. filtrationfiltered through sintered funnel
4. washwashed with acetone
5. customSolvent was removed