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HRID537208

反应详情

EQUATION

反应方程式

HRID 537208 的结构方程式

REACTANTS

反应物

3
结构：BrCc1ccccc1
HCID7498

alpha-Bromotoluene

C7H7Br

结构：C[Si](C)(C)[N-][Si](C)(C)C.[Li+]
HCID2733832

Lithium Hexamethyldisilazide

C6H18LiNSi2

结构：COC(=O)CCN1CCC(F)(c2ccc(Cl)cc2)CC1
HCID67462732

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)C(Cc1ccccc1)(Cc1ccccc1)CN1CCC(F)(c2ccc(Cl)cc2)CC1
HCID67468586

未命名化合物

收率 38%

PROCEDURE

实验过程

This compound was prepared from methyl 3-[4-(4-chlorophenyl)-4-fluoropiperidin-1-yl]propionate and 2.5 equivalents of both lithium hexamethyldisilazide and benzyl bromide as described in Step 2 of Example 4 in 38% yield.