Potassium Carbonate → HCID 54312464, compound

HRID 542695Notes

Reaction equation

HRID 542695 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([C:14]3[S:15][CH:16]=[CH:17][CH:18]=3)=[CH:10][N:9]=2)=[CH:4][CH:3]=1.C([O-])([O-])=O.[K+].[K+].[CH2:25](I)[CH2:26][CH2:27][CH2:28][CH2:29][CH3:30]>CN(C=O)C>[CH2:25]([O:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:13]=[CH:12][C:11]([C:14]3[S:15][CH:16]=[CH:17][CH:18]=3)=[CH:10][N:9]=2)=[CH:6][CH:7]=1)[CH2:26][CH2:27][CH2:28][CH2:29][CH3:30]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 125271-IodohexaneHCID 136023524HCID 136023524, compound

Product 1

HCID 54312464HCID 54312464, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Conditions

Temperature
80 °C

Procedure

A mixture of 15.3 g of 2-(2-p-hydroxyphenyl-5-pyridyl)-thiophene, 6.9 g of K2CO3, 25 g of hexyl iodide and 250 ml of DMF is heated at 80° C. for 16 hours, with stirring, and then cooled and worked up in the customary manner. 2-(2-p-Hexoxyphenyl-5-pyridyl)-thiophene is obtained.

Workup

  1. temperaturecooled

Sources & evidence

ORD record
ord-36c9e6bea95d4b378578d5a7fca00fcf
Source dataset
uspto-grants-1987_04
Patent number
US04659503

Reaction notes

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