Ethyl Acetoacetate → HCID 13826845, compound

HRID 542771Notes

Reaction equation

HRID 542771 reaction equation
[S:1]1[CH:5]=[C:4]([CH:6]=O)[C:3]2[CH:8]=[CH:9][CH:10]=[CH:11][C:2]1=2.[C:12]([O:18][CH2:19][CH3:20])(=[O:17])[CH2:13][C:14]([CH3:16])=O.[OH-:21].[NH4+:22]>C(O)C>[S:1]1[CH:5]=[C:4]([CH:6]2[C:13]([C:12]([O:18][CH2:19][CH3:20])=[O:17])=[C:14]([CH3:16])[NH:22][C:14]([CH3:16])=[C:13]2[C:12]([O:18][CH2:19][CH3:20])=[O:21])[C:3]2[CH:8]=[CH:9][CH:10]=[CH:11][C:2]1=2

Participants

5

Reactant 3

HCID 8868Ethyl AcetoacetateHCID 14923Ammonium HydroxideHCID 2273281-Benzothiophene-3-carbaldehyde

Product 1

HCID 13826845HCID 13826845, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Following the procedure of Example 1B, 2.04 g of benzo[b]thiophene-3-carboxaldehyde, 3.2 ml of ethyl acetoacetate, and 1.5 ml of ammonium hydroxide were allowed to react in 15 ml of ethanol to provide 1.4 g of the desired title product, m.p. 139°-142° C.

Sources & evidence

ORD record
ord-c5eab1ec46694fc19a12d33dd0925dd1
Source dataset
uspto-grants-1987_04
Patent number
US04659717

Reaction notes

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