4-Chlorobenzaldehyde → HCID 53979452, compound

HRID 544163Notes

Reaction equation

HRID 544163 reaction equation
[CH3:1][C:2]1[O:3][C:4]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:5][C:6](=[O:8])[CH:7]=1.[Na].[Cl:16][C:17]1[CH:24]=[CH:23][C:20]([CH:21]=O)=[CH:19][CH:18]=1>[O-]CC.[Na+].C(O)C>[Cl:16][C:17]1[CH:24]=[CH:23][C:20]([CH:21]=[CH:1][C:2]2[O:3][C:4]([C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=3)=[CH:5][C:6](=[O:8])[CH:7]=2)=[CH:19][CH:18]=1

Participants

6

Reactant 3

HCID 77264-ChlorobenzaldehydeHCID 1205214H-Pyran-4-one, 2-methyl-6-phenyl-HCID 5360545Sodium

Product 1

HCID 53979452HCID 53979452, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolvent2×HCID 2723922Sodium ethoxideSolvent

Procedure

2-Methyl-6-phenyl-4H-pyran-4-one (3.7 g) was dissolved in sodium ethoxide solution prepared by dissolving sodium (0.46 g) in ethanol (50 ml). A solution of 4-chlorobenzaldehyde (5.6 g) in ethanol (50 ml) was added and the mixture was stirred at room temperature for 24 hours. The solid which formed was recrystallised from ethanol to give the title product (mp 169°-171° C.).

Workup

  1. customprepared
  2. customThe solid which formed
  3. customwas recrystallised from ethanol

Sources & evidence

ORD record
ord-b2a97e2621a4443692351c6fe12de40e
Source dataset
uspto-grants-1984_05
Patent number
US04448787

Reaction notes

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