Diethyl (ethoxymethylene)malonate → HCID 178469523, compound

HRID 544394Notes

Reaction equation

HRID 544394 reaction equation
CCO[CH:4]=[C:5]([C:11]([O:13]CC)=O)[C:6]([O:8][CH2:9][CH3:10])=[O:7].[CH3:16][C:17]1[CH:23]=[CH:22][C:20]([NH2:21])=[CH:19][CH:18]=1.C1(OC2C=CC=CC=2)C=CC=CC=1>>[CH3:16][C:17]1[CH:18]=[C:19]2[C:20](=[CH:22][CH:23]=1)[N:21]=[CH:4][C:5]([C:6]([O:8][CH2:9][CH3:10])=[O:7])=[C:11]2[OH:13]

Participants

4

Reactant 3

HCID 6871Diethyl (ethoxymethylene)malonateHCID 7583Diphenyl EtherHCID 7813p-Toluidine

Product 1

HCID 178469523HCID 178469523, compound

Procedure

Using the procedure of Example 2, ethyl ethoxymethylene malonate and 4-methyl-aniline were reacted and treated with phenyl oxide to obtain ethyl 6-methyl-4-hydroxy-3-quinoline-carboxylate melting at >260° C.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-c61c4401fff4415b8c3d0e05f33d5033
Source dataset
uspto-grants-1984_05
Patent number
US04450166

Reaction notes

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