反应详情

The title compound of Example 1, Step A (0.97 g, 3 mmol) was treated with 50 mL of chloroform containing 3% each of TFA and triethylsilane for 2 h. The reaction was partitioned between aq sodium bicarbonate and EtOAc. The organic phase was concentrated and the resultant residue was purified by flash chromatography on silica gel (mobile phase=15:85 (v/v) EtOAc:hexanes) to provide the title compound.

1. customThe reaction was partitioned between aq sodium bicarbonate and EtOAc
2. concentrationThe organic phase was concentrated
3. customthe resultant residue was purified by flash chromatography on silica gel (mobile phase=15:85 (v/v) EtOAc:hexanes)