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HRID54689

反应详情

EQUATION

反应方程式

HRID 54689 的结构方程式

REACTANTS

反应物

2
结构：O=C(CBr)c1ccccc1
HCID6259

2-Bromoacetophenone

C8H7BrO

结构：OCCNc1nc2ccccc2[nH]1
HCID583867

2-(1H-Benzimidazol-2-ylamino)ethanol

C9H11N3O

PRODUCTS

生成物

1
结构：Br.Br.O=C(Cn1c(NCCO)nc2ccccc21)c1ccccc1
HCID19040800

未命名化合物

收率 89%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)O
溶剂HCID3776

Isopropanol

C3H8O

PROCEDURE

实验过程

Heat at reflux for three hours 8.95 g (50 mmol) of 2-(2-hydroxyethylamino)benzimidazole and 10 g of phenacyl bromide in 100 ml of 2-propanol. Allow to cool. Suction-filter the resulting precipitate and wash with acetone. The title compound is obtained.

WORKUP

后处理

  1. temperatureHeat
  2. temperatureto cool
  3. filtrationSuction-filter the resulting precipitate
  4. washwash with acetone