Triethylamine → HCID 178487132, compound

HRID 557138Notes

Reaction equation

HRID 557138 reaction equation
[I-:1].[CH3:2][O:3][C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][CH:13]=1)[N+:10]([CH3:14])=[C:9]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[N:8]=[C:7]2SC.[I-].[F:24][C:25]1[CH:26]=[CH:27][C:28]2[S:32][C:31]([CH3:33])=[N+:30]([CH3:34])[C:29]=2[CH:35]=1.C(N(CC)CC)C>CN(C)C=O>[I-:1].[F:24][C:25]1[CH:26]=[CH:27][C:28]2[S:32][C:31]([CH:33]=[C:7]3[C:6]4[C:11](=[CH:12][CH:13]=[C:4]([O:3][CH3:2])[CH:5]=4)[N:10]([CH3:14])[C:9]([C:15]4[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=4)=[N:8]3)=[N+:30]([CH3:34])[C:29]=2[CH:35]=1

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 669907845-Fluoro-2,3-dimethyl-benzothiazol-3-ium iodideHCID 669915126-Methoxy-1-methyl-4-methylsulfanyl-2-phenyl-quinazolin-1-ium iodide

Product 1

HCID 178487132HCID 178487132, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Conditions

Temperature
80 °C

Procedure

600 mg (1.41 mmol) 6-Methoxy-1-methyl-4-methylsulfanyl-2-phenyl-quinazolin-1-ium iodide and 436 mg (1.41 mmol) 5-fluoro-2,3-dimethyl-benzothiazol-3-ium iodide were dissolved in 3.0 ml dimethylformamide and 571 mg (0.79 ml, 5.64 mmol) triethylamine were added. The solution was stirred for 1 h at 80° C., filtrated and the residue was washed with water and methanol.

Workup

  1. filtrationfiltrated
  2. washthe residue was washed with water and methanol

Sources & evidence

ORD record
ord-34effdcaad544c3888d53f004b9d8346
Source dataset
uspto-grants-2011_11
Patent number
US08058431B2

Reaction notes

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