Triethylamine → HCID 178479927, compound

HRID 557145Notes

Reaction equation

HRID 557145 reaction equation
[I-:1].[CH3:2][N+:3]1[C:8]2[CH:9]=[CH:10][S:11][C:7]=2[C:6](SC)=[N:5][C:4]=1[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.[I-].[CH3:21][C:22]1[S:23][C:24]2[CH:31]=[CH:30][CH:29]=[CH:28][C:25]=2[N+:26]=1[CH3:27].C(N(CC)CC)C>CN(C)C=O>[I-:1].[CH3:27][N+:26]1[C:25]2[CH:28]=[CH:29][CH:30]=[CH:31][C:24]=2[S:23][C:22]=1[CH:21]=[C:6]1[N:5]=[C:4]([C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=2)[N:3]([CH3:2])[C:8]2[CH:9]=[CH:10][S:11][C:7]1=2

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 4591212,3-Dimethylbenzo[d]thiazol-3-ium iodideHCID 669910721-Methyl-4-methylsulfanyl-2-phenyl-thieno(3,2-d)pyrimidin-1-ium iodide

Product 1

HCID 178479927HCID 178479927, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Conditions

Temperature
80 °C

Procedure

200 mg (0.50 mmol) 1-Methyl-4-methylsulfanyl-2-phenyl-thieno(3,2-d)pyrimidin-1-ium iodide and 145 mg (0.50 mmol) 2,3-dimethyl-benzothiazol-3-ium iodide were dissolved in 2.0 ml dimethylformamide and 202 mg (0.28 ml, 2.00 mmol) triethylamine were added. The green solution was stirred for 1 h at 80° C., filtrated and the residue was washed with methanol. The crude product was purified further by HPLC.

Workup

  1. filtrationfiltrated
  2. washthe residue was washed with methanol
  3. customThe crude product was purified further by HPLC

Sources & evidence

ORD record
ord-0b7bf2fe6bb64c30b153690c4d80d56b
Source dataset
uspto-grants-2011_11
Patent number
US08058431B2

Reaction notes

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