反应详情

A solution of α-methylbenzylamine (8.37 g, 0.07 mol) and bromoacetaldehyde dimethylacetal (11.67 g, 0.07 mol) in acetonitrile (150 ml) containing potassium carbonate (12.39 g, 0.09 mol) was heated at reflux for 2d and cooled. The solid was filtered off and the filtrate was concentrated under reduced pressure to leave an oil. Chromatography on silica gel eluting with ethyl acetate afforded the title compound as an oil.

1. temperaturewas heated
2. temperaturecooled
3. filtrationThe solid was filtered off
4. concentrationthe filtrate was concentrated under reduced pressure
5. customto leave an oil